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(8) Furthermore, FOXO4's role in the IIS pathway suggests it might modulate the actions of diet and environmental factors on cell aging, acting as a mediator between external factors and cellular longevity pathways

In contrast, more recent studies in the Chinese population suggest substantially higher prevalence rates, ranging from 37.2% [147] to 50.8% [103, 144]

McColgan P, Tabrizi SJ (2018) Huntingtons disease: a clinical review

Transcriptome analysis reveals dysregulation of inflammatory and neuronal function in dorsal root ganglion of paclitaxel-induced peripheral neuropathy rats